Article

Genomic dissection and mutation-specific target discovery for breast cancer <i>PIK3CA</i> hotspot mutations

2024-01-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Recent advancements in high-throughput genomics and targeted therapies have provided tremendous potential to identify and therapeutically target distinct mutations associated with cancers. However, to date the majority of targeted therapies are used to treat all functional mutations within the same gene, regardless of affected codon or phenotype. <h4>Results</h4> In this st...

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Literature Corpus work: 15d6b274-4cbd-5766-b718-d93f34d2e3bc
DOI: 10.1101/2024.01.03.574067

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