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Article

Mutational landscape of pan-cancer patients with PIK3CA alterations in Chinese population.

BMC medical genomics - 1 Jul 2022

Huang Qingfeng, Zhou Yang, Wang Bowen, Zhao Yi, Zhang Fengxia, Ding Bowen

Abstract excerpt

PURPOSE: To analyze the mutational landscape of pan-cancer patients with PIK3CA mutations in Chinese population in real-world. METHODS: We analyzed PIK3CA mutation status in sequencing data of cell-free DNA from plasma and genomic DNA from matched peripheral blood lymphocyte in 11,904 Chinese pan-cancer patients, and compared them with genomic data from the Catalogue of Somatic Mutations in Cancer (COSMIC)...

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Identifiers

PMID: 35778737
DOI: 10.1186/s12920-022-01297-7
PMCID: PMC9248192

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