Article

Comparative characterization of OncoPro™ and Wnt-Based media reveals distinct phenotypic and pharmacologic states in patient-derived tumor organoids

2025-12-16

Abstract excerpt

<h4>Background</h4> Patient-derived tumor organoids (PDTOs) are strongly influenced by culture medium. We compared OncoPro™ (OP) Tumoroid Culture medium with conventional Wnt/R-spondin/noggin (Wnt) medium. This recently developed OP medium offers a standardized, serum-free alternative to Wnt-based formulations. <h4>Methods</h4> We compared OP and Wnt media across 36 PDTO lines from various malignancies (colorect...

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Literature Corpus work: 15c3e5cf-2492-520e-9036-0ad0cffc3a34
DOI: 10.64898/2025.12.13.693944

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