Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt Stimulation and Inhibition in the Development and Phenotype of Patient-Derived Gallbladder Organoids.

Biology of the cell - 1 Jul 2026

Dutta Ankita, Guha Payel, Selvarajan Akshaya Vijayan, Chowdhury Nandita, Banerjee Pritha, Ghosh Shrabanti Sarkar, Shaw Archana Kumari, Ganguli Debdutta, Sunderam Uma, Roy Manas Kumar, Banerjee Sudeep, Srinivasan Rajgopal, Roy Paromita, Saha Vaskar, Dutta Anindita, GuhaSarkar Dwijit

Abstract excerpt

BACKGROUND: Gallbladder cancer (GBC) is a highly lethal malignancy with limited experimental models to study disease biology or evaluate therapeutic responses. Although canonical Wnt activation is commonly used for patient-derived organoid (PDO) development and expansion, gallbladder PDOs have also been generated under Wnt-inhibitory conditions. No comparative assessments have determined how Wnt pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Deoxycytidine
Share to Gallbladder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gallbladder Neoplasms

Share to Gemcitabine

Share to Organoids

Share to Pyridines

Share to Wnt Proteins

Share to Wnt Signaling Pathway

Source

Identifiers

PMID: 42388006
DOI: 10.1111/boc.70074

Genes

DKK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt Stimulation and Inhibition in the Development and Phenotype of Patient-Derived Gallbladder Organoids.PMID 42388006Read ↗

Wnt stimulation and inhibition in the development and phenotype of patient-derived gallbladder organoidsSemantic proximity Read ↗

Patient‐derived organoids for personalized gallbladder cancer modelling and drug screeningSemantic proximity Read ↗

Comparative characterization of OncoPro™ and Wnt-Based media reveals distinct phenotypic and pharmacologic states in patient-derived tumor organoidsSemantic proximity Read ↗

Gallbladder cholangiocyte organoidsSemantic proximity Read ↗

Insights into gallbladder cancer pathogenesis from a living organoid gallbladder cholangiocyte biorepositorySemantic proximity Read ↗

A guide for establishing patient-derived organoids from bile samples obtained during endoscopic procedures and performing gene expression knockdownSemantic proximity Read ↗

Establishment and drug screening of patient-derived extrahepatic biliary tract carcinoma organoidsSemantic proximity Read ↗

miRNAs orchestration of gallbladder cancer – Particular emphasis on diagnosis, progression and drug resistanceSemantic proximity Read ↗

Establishment and Drug Screening of Patient-Derived Extrahepatic Biliary Tract Carcinoma OrganoidsSemantic proximity Read ↗

Human extrahepatic and intrahepatic cholangiocyte organoids show region-specific differentiation potential and model cystic fibrosis-related bile duct diseaseSemantic proximity Read ↗

Cholangiocarcinoma Disease Modelling Through Patients Derived OrganoidsSemantic proximity Read ↗

An appendiceal cancer organoid biobank identifies phenotypic evolution and druggable dependencies of peritoneal carcinomatosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.