Article

Long-term maintenance of patient-specific characteristics in tumoroids from six cancer indications in a common base culture media system

2024-06-12

Abstract excerpt

Tumoroids, also known as cancer organoids, are patient-derived cancer cells grown as 3D, self-organized multicellular structures that maintain key characteristics (e.g., genotype, gene expression levels) of the tumor from which they originated. These models have emerged as valuable tools for studying tumor biology, cytotoxicity, and response of patient-derived cells to cancer therapies. However, the establishment...

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Literature Corpus work: b1e66319-bb8a-519b-ab69-e7f0bbee6a99
DOI: 10.1101/2024.06.10.598331

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