Article

Wnt stimulation and inhibition in the development and phenotype of patient-derived gallbladder organoids

2026-04-07

Abstract excerpt

Gallbladder cancer (GBC) is a highly lethal malignancy with limited experimental models to study disease biology or evaluate therapeutic responses. Although canonical Wnt activation is commonly used for patient-derived organoid (PDO) development and expansion, gallbladder PDOs has also been generated under Wnt-inhibitory conditions. No comparative assessment has determined how Wnt pathway modulation influences gal...

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Literature Corpus work: 0bb1ab91-ffda-5ac6-9f69-f412d5ab7f73
DOI: 10.64898/2026.04.06.716840

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