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Patient-derived organoids in translational oncology and drug screening

13 Apr 2023

Abstract excerpt

Patient-derived organoids (PDO) are a new biomedical research model that can reconstruct phenotypic and genetic characteristics of the original tissue and are useful for research on pathogenesis and drug screening. To introduce the progression in this field, we review the key factors of constructing organoids derived from epithelial tissues and cancers, covering culture medium and matrix, morphological...

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PMID: 37061121
DOI: 10.1016/j.canlet.2023.216180

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