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A high-throughput 3D culture microfluidic platform for multi-parameter phenotypic and omics profiling of patient-derived organoids

2024-12-29

Abstract excerpt

Patient-derived organoids (PDOs) are poised to become central tools both in clinical practice, to preemptively identify patient optimal treatments, and in drug discovery, overcoming the limitations of cancer cell lines. However, the use of PDOs in these settings has been hampered by several bottlenecks, including sample requirements, assay time, and handling in the context of high-throughput assays. We developed a...

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Literature Corpus work
db3f4893-0148-5650-8760-d587ebf7fe6e
DOI
10.1101/2024.12.28.630600
Open publication

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A high-throughput 3D culture microfluidic platform for multi-parameter phenotypic and omics profiling of patient-derived organoidsDOI 10.1101/2024.12.28.630600
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