Article

Evolution of regulatory signatures in primate cortical neurons at cell type resolution

2020-07-27

Abstract excerpt

<h4>ABSTRACT</h4> The human cerebral cortex contains many cell types that likely underwent independent functional changes during evolution. However, cell type-specific regulatory landscapes in the cortex remain largely unexplored. Here we report epigenomic and transcriptomic analyses of the two main cortical neuronal subtypes, glutamatergic projection neurons and GABAergic interneurons, in human, chimpanzee and r...

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Literature Corpus work: 15a70333-9a2c-5b4e-9458-75616400f561
DOI: 10.1101/2020.07.24.219881

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