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A general principle of neuronal evolution reveals a human-accelerated neuron type potentially underlying the high prevalence of autism in humans

2024-08-03

Abstract excerpt

The remarkable ability of a single genome sequence to encode a diverse collection of distinct cell types, including the thousands of cell types found in the mammalian brain, is a key characteristic of multicellular life. While it has been observed that some cell types are far more evolutionarily conserved than others, the factors driving these differences in evolutionary rate remain unknown. Here, we hypothesized...

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Literature Corpus work
cd5d80e1-100d-5599-a585-4c6a6201e67a
DOI
10.1101/2024.08.02.606407
Open publication

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A general principle of neuronal evolution reveals a human-accelerated neuron type potentially underlying the high prevalence of autism in humansDOI 10.1101/2024.08.02.606407
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