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The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus

29 Aug 2013

Abstract excerpt

Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus which establishes latent infection in endothelial and B cells, as well as in primary effusion lymphoma (PEL). During latency, the viral genome exists as a circular DNA minichromosome (episome) and is packaged into chromatin analogous to human chromosomes. Only a small subset of promoters, those which drive latent RNAs, are active in...

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PMID: 23986576
DOI: 10.1128/jvi.01685-13

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The Open Chromatin Landscape of Kaposi's Sarcoma-Associated HerpesvirusPMID 23986576Read ↗

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Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus LatencySemantic proximity Read ↗

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Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma TissuesSemantic proximity Read ↗

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LANA Binds to Multiple Active Viral and Cellular Promoters and Associates with the H3K4Methyltransferase hSET1 ComplexSemantic proximity Read ↗

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