Article

Dynamic neuro-immune regulation of psychiatric risk loci in human neurons

2024-07-09

Abstract excerpt

<h4>ABSTRACT</h4> The immune environment influences neurodevelopment and subsequent clinical trajectories for psychiatric outcomes in childhood and adolescence. Yet it remains unclear if the impact of maternal and fetal immune activation varies with distinct polygenic risk profiles. Therefore, here we catalogue genotype and environment (GxE) interactions, contrasting allele-specific regulatory activity between in...

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Literature Corpus work: 153fd63e-3e10-58a5-bd67-6c126be7d13b
DOI: 10.1101/2024.07.09.602755

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