Article

Human genetic variation shapes the response of neurons to interferons

2025-05-28

Abstract excerpt

Inflammation is increasingly recognized as important to neuropathology, including more classic neuroimmune disease as well as neurodegenerative and neuropsychiatric disorders. Interferons (IFN) are important mediators of central nervous system inflammation. Individuals appear to vary in susceptibility to neuroinflammatory pathology, suggesting that identifying human genetic modifiers of the neuronal IFN response m...

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Literature Corpus work: 5824597f-8a48-5285-9507-f9d5536d7302
DOI: 10.1101/2025.05.28.653507

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