Article

Blocking the MIF-CD74 axis augments radiotherapy efficacy for brain metastasis in NSCLC via synergistically promoting microglia M1 polarization

2023-11-08

Abstract excerpt

<title>Abstract</title> <p>Background Brain metastasis is one of the main causes of recurrence and death in non-small cell lung cancer (NSCLC). Although radiotherapy is the main local therapy for brain metastasis, it is inevitable that some cancer cells become resistant to radiation. Microglia, as macrophages colonized in the brain, play an important role in the tumor microenvironment. Our previous study demonst...

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Literature Corpus work: 14c7f7f7-fa12-5736-a0b8-d81b0276d919
DOI: 10.21203/rs.3.rs-3520330/v1

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