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Article

Microglia-glioma cross-talk: a two way approach to new strategies against glioma.

Frontiers in bioscience (Landmark edition) - 1 Jan 2017

Arcuri Cataldo, Fioretti Bernard, Bianchi Roberta, Mecca Carmen, Tubaro Claudia, Beccari Tommaso, Franciolini Fabio, Giambanco Ileana, Donato Rosario

Abstract excerpt

Glioblastoma (GBM) is the most malignant and aggressive among primary brain tumors, characterized by very low life expectancy. In vivo, glioma and glioblastoma in particular contain large numbers of immune cells (myeloid cells) such as microglia and tumour-infiltrating macrophages (or glioma associated macrophages). These glioma-infiltrating myeloid cells comprise up to 30% of total tumor mass and have been...

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Brain Neoplasms
Cell Communication
Glioma
Immune Tolerance
Microglia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myeloid-Derived Suppressor Cells

Neoplastic Stem Cells

Tumor Microenvironment

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PMID: 27814616
DOI: 10.2741/4486

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