Article

Characterisation of immune cell subsets of tumour infiltrating lymphocytes in brain metastases

2021-02-11

Abstract excerpt

The heterogeneity of tumor infiltrating lymphocytes is not well characterized in brain metastasis. To address this, we performed a targeted analysis of immune cell subsets in brain metastasis tissues to test which immunosuppressive routes are involved in brain metastasis. We performed multiplex immunofluorescence (mIF), using commercially available validated antibodies on twenty formalin-fixed paraffin embedded wh...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d994e48d-8689-5c0a-992a-35d42796a613
DOI: 10.1101/2021.02.10.430531

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterisation of immune cell subsets of tumour infiltrating lymphocytes in brain metastasesDOI 10.1101/2021.02.10.430531Read

MET receptor activation by stromal cells serves as promising target in melanoma brain metastasesSemantic proximity Read

The CD8 <sup>+</sup> T cell landscape of human brain metastasesSemantic proximity Read

Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune CellsSemantic proximity Read

Cellular architecture of human brain metastases.Semantic proximity Read

Cellular and Molecular Changes of Brain Metastases-Associated Myeloid Cells during Disease Progression and Therapeutic ResponseSemantic proximity Read

Microenvironmental Heterogeneity in Brain MalignanciesSemantic proximity Read

Tumor-Associated Macrophages in Meningiomas: An Independent Prognostic Factor for Poor Survival Outperforming the Benefits of T cellsSemantic proximity Read

Identification and characterization of tertiary lymphoid structures in brain metastasesSemantic proximity Read

Single-cell map of diverse immune phenotypes in the metastatic brain tumor microenvironment of nonsmall-cell lung cancerSemantic proximity Read

Unraveling the Enigma of Melanoma Brain Metastasis: New Horizons in Mechanisms, Diagnosis, and TherapySemantic proximity Read

Immune Subtypes and Survival in Patients with Primary GliomaSemantic proximity Read

Distinct phenotypic states and spatial distribution of CD8+ T cell clonotypes in human brain metastasesSemantic proximity Read