Article

Irradiation-induced M1 Microglia Affect Brain Metastatic Colonization of A549 Cell Lines via miR-9/CDH1 Axis

2020-12-11

Abstract excerpt

<title>Abstract</title> <p><bold>Background and purpose: </bold>Brain metastasis is among the leading causes of death in patients with non-small-cell lung cancer (NSCLC). Through yet unknown mechanisms, prophylactic cranial irradiation (PCI) can significantly decrease the incidence of brain metastases. We propose that PCI probably exerts indirect anti-tumoral effects by turning cerebral “soil” unfavorable for the...

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Literature Corpus work: 5cad4c03-8712-58ac-b6d1-807cdbf8d961
DOI: 10.21203/rs.3.rs-123435/v1

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