Back to search

Article

Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal Injuries

2018-07-12

Abstract excerpt

Reactive microglia and infiltrating peripheral monocytes have been implicated in many neurodegenerative diseases of the retina and central nervous system (CNS). However, their specific contribution in retinal degeneration remains unclear. We recently showed that peripheral monocytes that infiltrate the retina after ocular injury in mice become permanently engrafted into the tissue, establishing a pro-inflammatory...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
145ab2cc-6409-5ac2-85a2-ca5facba639d
DOI
10.1101/366310
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal InjuriesDOI 10.1101/366310
Infiltrating monocytes augment alternative complement activation and exacerbate inherited retinal degeneration in a mouse modelSemantic proximity
Structural and functional distinctions of co-resident microglia and monocyte-derived macrophages after retinal degenerationSemantic proximity
Deciphering perivascular macrophages and microglia in the retinal ganglion cell layersSemantic proximity
Immunological Landscape of Retinal Ischemia-Reperfusion Injury: Insights into Resident and Peripheral Immune Cell ResponsesSemantic proximity
Corticosteroids prevent pathological angiogenesis yet compromise reparative vascular remodeling in the retinaSemantic proximity
Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retinaSemantic proximity
The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisationSemantic proximity
RasV12 Expression in Microglia Promotes Retinal Inflammatory Circuits and Impairment of PhotoreceptorSemantic proximity
Microglial Cell Dysfunction in CRB1-Associated Retinopathies.Semantic proximity
IL-1 Family Members Mediate Cell Death, Inflammation and Angiogenesis in Retinal Degenerative DiseasesSemantic proximity
Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by MicrogliaSemantic proximity
Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal modelSemantic proximity
Select a neighboring publication to make it the new centre.