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Article

Microglial Cell Dysfunction in CRB1-Associated Retinopathies.

Advances in experimental medicine and biology - 1 Jan 2019

Alves C Henrique, Wijnholds Jan

Abstract excerpt

Inherited retinal diseases encompass a large group of clinically and genetically heterogeneous diseases estimated to affect two million people worldwide. Among these people, approximately 80,000 are or will become blind in their first decades of life due to mutations in both alleles of the Crumbs homologue-1 (CRB1) gene. Microglia are the resident immune surveyor cells in the retina, and their roles have been...

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Identifiers

PMID: 31884605
DOI: 10.1007/978-3-030-27378-1_26

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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