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Article

Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia

15 Jan 2019

Abstract excerpt

Microglia play important roles in shaping the developing CNS, and at early stages they have been proposed to regulate progenitor proliferation, differentiation, and neuronal survival. However, these studies reveal contradictory outcomes, highlighting the complexity of these cell–cell interactions. Here, we investigate microglia function during embryonic mouse retina development, where only microglia, progenitors,...

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PMID: 30647151
DOI: 10.1523/jneurosci.1854-18.2018

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