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Article

The role of interferon regulatory factor 8 for retinal tissue homeostasis and development of choroidal neovascularisation

20 Sept 2021

Abstract excerpt

BACKGROUND: Microglia cells represent the resident innate immune cells of the retina and are important for retinal development and tissue homeostasis. However, dysfunctional microglia can have a negative impact on the structural and functional integrity of the retina under native and pathological conditions. METHODS: In this study, we examined interferon-regulatory factor 8 (Irf8)-deficient mice to determine the...

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PMID: 34544421
DOI: 10.1186/s12974-021-02230-y

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