Article

Rapid <i>in vitro</i> prototyping of O-methyltransferases for pathway applications in <i>Escherichia coli</i>

2020-08-27

Abstract excerpt

O-methyltransferases are ubiquitous enzymes involved in biosynthetic pathways for secondary metabolites such as bacterial antibiotics, human catecholamine neurotransmitters, and plant phenylpropanoids. While thousands of putative O-methyltransferases are found in sequence databases, few examples are functionally characterized. From a pathway engineering perspective, however, it is crucial to know the substrate and...

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Literature Corpus work: 14297a86-b696-5e71-9935-0a9d5d47a982
DOI: 10.1101/2020.08.27.258715

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