Article

Model-driven exploration of underground metabolism reveals drivers of metabolic innovation in <i>Pseudomonas putida</i>

2025-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Beyond the heterologous expression of genes to generate microbes with novel properties, evolutionary engineering offers a complementary approach by exploiting adaptive processes to refine and expand cellular functionalities in biotechnology. A promising source for the generation of novel metabolic functions is the so-called underground metabolism, i.e., the subnetwork conformed by catalytically...

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Literature Corpus work: 2dcfae23-18b2-5cf2-8e46-6b611935e2a8
DOI: 10.64898/2025.12.09.693157

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