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Article

Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviour.

Human molecular genetics - 15 Feb 2015

Breda Carlo, Nugent Marie L, Estranero Jasper G, Kyriacou Charalambos P, Outeiro Tiago F, Steinert Joern R, Giorgini Flaviano

Abstract excerpt

A central pathological hallmark of Parkinson's disease (PD) is the presence of proteinaceous depositions known as Lewy bodies, which consist largely of the protein α-synuclein (aSyn). Mutations, multiplications and polymorphisms in the gene encoding aSyn are associated with familial forms of PD a...

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Source

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Identifiers

PMID: 25305083
DOI: 10.1093/hmg/ddu521
PMCID: PMC4986550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25305083-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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