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Article

Systematic discovery of Rab GTPases with synaptic functions in Drosophila.

Current biology : CB - 25 Oct 2011

Chan Chih-Chiang, Scoggin Shane, Wang Dong, Cherry Smita, Dembo Todd, Greenberg Ben, Jin Eugene Jennifer, Kuey Cansu, Lopez Antonio, Mehta Sunil Q, Perkins Theodore J, Brankatschk Marko, Rothenfluh Adrian, Buszczak Michael, Hiesinger P Robin

Abstract excerpt

BACKGROUND: Neurons require highly specialized intracellular membrane trafficking, especially at synapses. Rab GTPases are considered master regulators of membrane trafficking in all cells, and only very few Rabs have known neuron-specific functions. Here, we present the first systematic characterization of neuronal expression, subcellular localization, and function of Rab GTPases in an organism with a brain....

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Identifiers

PMID: 22000105
DOI: 10.1016/j.cub.2011.08.058
PMCID: PMC3351199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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