Article

Single-cell transcriptome profiling reveals neutrophil heterogeneity and orchestrated maturation during homeostasis and bacterial infection

2019-10-04

Abstract excerpt

<h4>Summary</h4> The full neutrophil heterogeneity and differentiation landscape remains incompletely characterized. Here we profiled >25,000 differentiating and mature mouse neutrophils using single-cell RNA sequencing to provide a comprehensive transcriptional landscape of neutrophil maturation, function, and fate decision in their steady state and during bacterial infection. Eight neutrophil populations were d...

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Literature Corpus work: 9ac98359-2811-5564-8ed4-38df0531a2ae
DOI: 10.1101/792200

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