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Article

Engineering Antibody-Drug Conjugates targeting an Adhesion GPCR, CD97

2025-08-28

Abstract excerpt

<h4>ABSTRACT</h4> Adhesion G protein-coupled receptors (aGPCRs) are key cell-adhesion molecules involved in many cellular functions and contribute to human diseases, including cancer. aGPCRs are characterized by large extracellular regions that could serve as readily accessible antigens. However, the potential of aGPCRs as targets for biologic therapeutics has not been extensively explored. CD97, also known as AD...

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Identifiers and source

Literature Corpus work
139d1ae1-054b-5ccb-9e09-73becadcc60a
DOI
10.1101/2025.08.24.671942
Open publication

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Engineering Antibody-Drug Conjugates targeting an Adhesion GPCR, CD97DOI 10.1101/2025.08.24.671942
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