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A Decade of Clinical Experience with DARPins in Oncology and Virology: A Systematic Review

2025-05-22

Abstract excerpt

DARPins (Designed Ankyrin Repeat Proteins) are a non-antibody based protein scaffold which has undergone extensive clinical characterization. DARPins are small, stable proteins derived from naturally occurring ankyrin repeat proteins and are characterized by high binding affinity and specificity, and a flexible architecture enabling multispecific approaches beyond bi-specific molecules. A total of seven clinical D...

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Identifiers and source

Literature Corpus work
d54eff00-6876-5af0-97df-884bad2b525b
DOI
10.1101/2025.05.21.25328103
Open publication

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A Decade of Clinical Experience with DARPins in Oncology and Virology: A Systematic ReviewDOI 10.1101/2025.05.21.25328103
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