Article

LGR5 targeting molecules as therapeutic agents for multiple cancer types

2022-09-02

Abstract excerpt

Leucine-rich repeat-containing G-protein receptor 5 (LGR5) has been characterised as a stem cell and cancer stem cell marker. Previous analyses of LGR5 transcript levels indicate high level expression discriminates malignancies such as colorectal cancer (CRC) and pre-B acute lymphoblastic leukaemia (pre-B ALL) from healthy tissues suggesting LGR5 protein expression may provide a molecular handle for prognosis and...

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Literature Corpus work: 66626cb4-4ddc-5bcc-8777-a0c4fbdc29ea
DOI: 10.1101/2022.09.01.506182

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