Article

Functional targeting of Glypican-4 by a conformation-specific single-domain antibody

2025-05-15

Abstract excerpt

<h4>ABSTRACT</h4> The heparan sulphate proteoglycan, Glypican-4 (GPC-4), is an integral component of cell surfaces that fulfils key functions as a modulator of cell communication. Over time, human GPC-4 (hGPC4) has gained recognition as a valuable target for enhancing the therapeutic potential of human pluripotent stem cells (hPSCs). hGPC-4 is also a promising diagnostic and therapeutic target for a range of deve...

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Literature Corpus work: 49d8f46f-4674-5e2a-8aa1-353cf2058bec
DOI: 10.1101/2025.05.10.653258

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