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Article

CD97 is a multifunctional leukocyte receptor with distinct roles in human cancers

22 Aug 2013

Abstract excerpt

G-protein coupled receptors (GPCRs) represent the most diverse and biologically ubiquitous protein receptors. The epidermal growth factor seven-span transmembrane (EGF-TM7) family consists of adhesion GPCRs with a diverse functional repertoire. CD97 is the most broadly expressed member with roles in cell adhesion, migration and regulation of intercellular junctions. CD97 is also expressed in a variety of human...

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PMID: 23969601
DOI: 10.3892/ijo.2013.2075

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