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Article

A review of antibody-based therapeutics targeting G protein-coupled receptors: an update

8 Apr 2020

Abstract excerpt

INTRODUCTION: G protein-coupled receptors (GPCRs) play key roles in many biological functions and are linked to many diseases across all therapeutic areas. As such, GPCRs represent a significant opportunity for antibody-based therapeutics. AREAS COVERED: The structure of the major GPCR families is summarized in the context of choice of antigen source employed in the drug discovery process and receptor biology...

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PMID: 32264722
DOI: 10.1080/14712598.2020.1745770

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