Article

snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues

2024-09-24

Abstract excerpt

Profiling cellular heterogeneity in formalin-fixed paraffin-embedded (FFPE) tissues is key to characterizing clinical specimens for biomarkers, therapeutic targets, and drug responses. Recent advancements in single-nucleus RNA sequencing (snRNA-seq) techniques tailored for FFPE tissues have demonstrated their feasibility. However, isolation of high-quality nuclei from FFPE tissue with current methods remains chall...

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Literature Corpus work: 135c1575-8d1d-5fee-a916-c0063c2512a6
DOI: 10.1101/2024.09.20.614201

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