Article

A single-cell and single-nucleus RNA-seq toolbox for fresh and frozen human tumors

2019-09-12

Abstract excerpt

Single cell genomics is essential to chart the complex tumor ecosystem. While single cell RNA-Seq (scRNA-Seq) profiles RNA from cells dissociated from fresh tumor tissues, single nucleus RNA-Seq (snRNA-Seq) is needed to profile frozen or hard-to-dissociate tumors. Each strategy requires modifications to fit the unique characteristics of different tissue and tumor types, posing a barrier to adoption. Here, we devel...

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Literature Corpus work: 24bae607-bac3-58aa-a018-ef68d0e8bc85
DOI: 10.1101/761429

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