Article

Nuclei multiplexing with barcoded antibodies for single-nucleus genomics

2018-11-23

Abstract excerpt

Single-nucleus RNA-Seq (snRNA-seq) enables the interrogation of cellular states in complex tissues that are challenging to dissociate, including frozen clinical samples. This opens the way, in principle, to large studies, such as those required for human genetics, clinical trials, or precise cell atlases of large organs. However, such applications are currently limited by batch effects, sequential processing, and...

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Literature Corpus work: aef3db3a-031b-53ab-bdb4-66b284c73e1b
DOI: 10.1101/476036

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