Article

Adiposity-Associated Monocyte Costimulatory Programming in Rheumatoid Arthritis Identified by Single-Cell Transcriptomics

2026-06-12

Abstract excerpt

<h4>Background</h4> Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease which can lead to progressive disability and damage to multiple organs. Obesity is associated with higher disease activity in RA and inadequate long-term outcomes, so better understanding of mechanisms linking adiposity to immune dysregulation might help to refine optimal treatments. Monocytes are important contributors to im...

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Literature Corpus work: 134981e1-9e9c-5eae-b9ae-968e3641eb6d
DOI: 10.64898/2026.06.09.26355275

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