Article

Trained immunity in human monocyte enhances myeloid-T-cell pathogenic crosstalk in Ankylosing Spondylitis

2023-06-10

Abstract excerpt

Recent studies in infectious, cardiovascular and neurodegenerative diseases have established the presence of memory in innate immune cells. This “trained immunity (TI)” leads to an enhanced response to a second challenge. Monocytes in Ankylosing Spondylitis (AS), a common form of inflammatory arthritis, are known to be hyper-responsive to microbial stimulus lipopolysaccharide (LPS). We asked if TI is present in AS...

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Literature Corpus work: 391b9095-9083-5295-8bb8-272f536238d5
DOI: 10.1101/2023.06.10.544264

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