Article

Defective Macrophage Plasticity Exacerbates Progression of Inflammation in Patients with Rheumatoid Arthritis

2026-03-27

Abstract excerpt

<title>Abstract</title> <p>Background Rheumatoid Arthritis (RA), along with other inflammatory arthritides, affects over 1% of the global population. There are no cures, and only 20% of patients achieve 2-year drug-free remission. Importantly, recent studies show that macrophages have a dual role in synovial inflammation due to the existence of proinflammatory subsets (M1) and remission-associated macrophages (M...

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Literature Corpus work: e00584aa-6d67-531f-a155-7fcefab8cbe0
DOI: 10.21203/rs.3.rs-9096264/v1

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