Article

Metabolic-secretory decoupling defines a disease-intrinsic state in rheumatoid arthritis monocytes

2026-04-27

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Circulating monocytes from rheumatoid arthritis (RA) patients are pre-primed for inflammatory activation, but their disease-intrinsic features have not been systematically characterized. Given the important role of metabolism in shaping immune cell function, we aimed to determine how this pre-primed state is underpinned metabolically and whether these changes persist across...

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Literature Corpus work: 8e243b47-bd62-51ea-98d3-75a57355ee74
DOI: 10.64898/2026.04.23.720351

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