Article

Deciphering Cell-types and Gene Signatures Associated with Disease Activity in Rheumatoid Arthritis using Single Cell RNA-sequencing

2023-10-06

Abstract excerpt

<h4>Objective</h4> Single cell profiling of synovial tissue has previously identified gene signatures associated with rheumatoid arthritis (RA) pathophysiology, but synovial tissue is difficult to obtain. This study leverages single cell sequencing of peripheral blood mononuclear cells (PBMCs) from patients with RA and matched healthy controls to identify disease relevant cell subsets and cell type specific signa...

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Literature Corpus work: 378b5256-6ee1-528f-89c7-c4d387b1132e
DOI: 10.1101/2023.10.05.560352

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