Article

<i>CR1</i>variants contribute to FSGS susceptibility across multiple populations

2023-11-20

Abstract excerpt

Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome with an annual incidence in the United States in African-Americans compared to European-Americans of 24 cases and 5 cases per million, respectively. Among glomerular diseases in Europe and Latin-America, FSGS was the second most frequent diagnosis, and in Asia the fifth. We expand previous efforts in understanding genetics of FSGS by...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 133b77a3-355a-5d03-a058-7b43f53c36d5
DOI: 10.1101/2023.11.20.23298462

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>CR1</i>variants contribute to FSGS susceptibility across multiple populationsDOI 10.1101/2023.11.20.23298462Read

A glomerular transcriptomic landscape of <i>APOL1</i> in Black patients with focal segmental glomerulosclerosisSemantic proximity Read

Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population.Semantic proximity Read

Genetics, Genomics, and Precision Medicine in End-Stage Kidney Disease.Semantic proximity Read

APOL1 Nephropathy: A Population Genetics and Evolutionary Medicine Detective Story.Semantic proximity Read

From GWAS to Translational Insights: Comprehensive Genetic Analysis of Nephrotic Syndrome from Multiple PopulationsSemantic proximity Read

Quantifying the genetic contributions in unexplained kidney failure reveals<i>APOL1-HLA</i>interactionSemantic proximity Read

Large-Scale Whole-Genome Sequencing Reveals the Genetic Architecture of Primary Membranoproliferative GN and C3 GlomerulopathySemantic proximity Read

Identification of Novel Genetic Risk Factors for Focal Segmental Glomerulosclerosis in Children: Results From the Chronic Kidney Disease in Children (CKiD) CohortSemantic proximity Read

Genome-wide Genotyping of Cerebral Cavernous Malformation Type 1 Individuals to Identify Genetic Modifiers of Disease Severity.Semantic proximity Read

Targeted NGS panel reveals a high burden of collagen IV, podocyte, and transcription factor gene mutations in biopsy-proven focal segmental glomerulosclerosisSemantic proximity Read

Local ancestry-aware genome-wide meta-analysis uncovers novel genetic loci for sickle cell disease nephropathySemantic proximity Read

Molecular Mechanisms of APOL1-Associated Kidney Disease.Semantic proximity Read