Article

Targeted NGS panel reveals a high burden of collagen IV, podocyte, and transcription factor gene mutations in biopsy-proven focal segmental glomerulosclerosis

2026-01-30

Abstract excerpt

<title>Abstract</title> <p>Background The genetic architecture of focal segmental glomerulosclerosis (FSGS), a primary cause of nephrotic syndrome and progressive kidney failure, is still poorly understood among Middle Eastern populations. Monogenic and oligogenic forms of hereditary kidney disease are expected to be common in these populations. This study investigated genotype-phenotype associations and charact...

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Literature Corpus work: 5486f518-632d-585e-a879-8b2aa4618503
DOI: 10.21203/rs.3.rs-8663234/v1

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Targeted NGS panel reveals a high burden of collagen IV, podocyte, and transcription factor gene mutations in biopsy-proven focal segmental glomerulosclerosisDOI 10.21203/rs.3.rs-8663234/v1Read

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