Article
Idiopathic collapsing glomerulopathy is associated with APOL1 high-risk genotypes or Mendelian variants in most affected individuals in a highly admixed population.
Kidney international - 1 Mar 2024
Neves Precil D, Watanabe Andreia, Watanabe Elieser H, Narcizo Amanda M, Nunes Kelly, Lerario Antonio M, Ferreira Frederico M, Cavalcante Lívia B, Wongboonsin Janewit, Malheiros Denise M, Jorge Lectícia B, Sampson Matthew G, Noronha Irene L, Onuchic Luiz F
Abstract excerpt
Collapsing glomerulopathy (CG) is most often associated with fast progression to kidney failure with an incidence apparently higher in Brazil than in other countries. However, the reason for this occurrence is unknown. To better understand this, we performed an integrated analysis of clinical, histological, therapeutic, causative genetic and genetic ancestry data in a highly genetically admixed cohort of 70...
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