Article

A glomerular transcriptomic landscape of <i>APOL1</i> in Black patients with focal segmental glomerulosclerosis

2021-02-20

Abstract excerpt

Apolipoprotein L1 ( APOL1 )-associated focal segmental glomerulosclerosis (FSGS) is the dominant form of FSGS in Black people. There are no targeted therapies for this condition, in part because the molecular mechanisms underlying APOL1’s pathogenic contribution to FSGS are incompletely understood. Studying the transcriptomic landscape of APOL1 FSGS in patient kidneys is an important way to discover genes and mole...

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Literature Corpus work: 397586fd-a7e5-5eb0-983c-c4bfa7109a20
DOI: 10.1101/2021.02.18.21251945

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