Article

HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells

2018-03-18

Abstract excerpt

Hypoxia stimulates metastasis in cancer and is linked to poor patient prognosis. In tumours, oxygen levels vary and hypoxic regions exist within a generally well-oxygenated tumour. However, whilst the heterogeneous environment is known to contribute to metastatic progression, little is known about the mechanism by which heterogeneic hypoxia contributes to cancer progression. This is largely because existing experi...

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Literature Corpus work: 132120bb-2547-57d5-acf2-8808f653e3be
DOI: 10.1101/266213

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