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Article

Hypoxia and cancer.

Journal of molecular medicine (Berlin, Germany) - 1 Dec 2007

Brahimi-Horn M Christiane, Chiche Johanna, Pouysségur Jacques

Abstract excerpt

A major feature of solid tumours is hypoxia, decreased availability of oxygen, which increases patient treatment resistance and favours tumour progression. How hypoxic conditions are generated in tumour tissues and how cells respond to hypoxia are essential questions in understanding tumour progression and metastasis. Massive tumour-cell proliferation distances cells from the vasculature, leading to a deficiency...

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Identifiers

PMID: 18026916
DOI: 10.1007/s00109-007-0281-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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