Article

<i>MAPK14</i> /p38α Shapes the Molecular Landscape of Endometrial Cancer and promotes Tumorigenic Characteristics

2024-06-29

Abstract excerpt

The molecular underpinnings of H igh G rade E ndometrial C arcinoma (HGEC) metastatic growth and survival are poorly understood. Here we show that ascites-derived and primary tumor HGEC cell lines in 3D spheroid culture faithfully recapitulate key features of malignant peritoneal effusion and exhibit fundamentally distinct transcriptomic, proteomic and metabolomic landscapes when compared with conventional 2D...

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Literature Corpus work: 12d8bbc1-4890-5c3a-9ebc-d45cb5f13587
DOI: 10.1101/2024.06.25.600674

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