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Understanding the assembly and function of the CoREST co-repressor complex

2019-01-01

Abstract excerpt

The CoREST complex was initially identified as a cofactor of the REST transcriptional repressor which plays important roles in regulating neuron-specific gene expression and neuronal stem cell fate. The CoREST complex contains several proteins including the histone deacetylases HDAC1 and HDAC2, the FADdependent demethylase LSD1 and the co-repressor protein CoREST. HDAC1, the first human HDAC identified, is only fo...

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Literature Corpus work
128eb8e4-5778-5e13-b81f-bd29bbbd0c60
DOI
10.25392/leicester.data.10298249.v1
Open publication

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