Article

Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions

2018-07-03

Abstract excerpt

<h4>Summary</h4> Genomic studies have identified hundreds of candidate genes near loci associated with risk for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologues of 132 human schizophrenia-associated genes and created a phenotype atlas consisting of whole-brain activity maps, brain structural differences, and profiles of behavioral abnormalities. Phenotypes were diverse but...

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Literature Corpus work: b7381d82-222f-5792-835e-a421ac4d7327
DOI: 10.1101/360677

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