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Article

Glutamate synapses in human cognitive disorders.

Annual review of neuroscience - 8 Jul 2015

Volk Lenora, Chiu Shu-Ling, Sharma Kamal, Huganir Richard L

Abstract excerpt

Accumulating data, including those from large genetic association studies, indicate that alterations in glutamatergic synapse structure and function represent a common underlying pathology in many symptomatically distinct cognitive disorders. In this review, we discuss evidence from human genetic studies and data from animal models supporting a role for aberrant glutamatergic synapse function in the etiology of...

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Identifiers

PMID: 25897873
DOI: 10.1146/annurev-neuro-071714-033821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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